Rehabilitation Pre-Transplant


  We highly recommend that each patient undergoes a pre-transplant functional capacity evaluation (please download assessment files from the link below) to help monitor and early detection of MSK manifestations post-HSCT.  It is recommended that the subjective evaluation should include, apart from the usual physical therapy (PT) assessment, the following:

  • Existing MSK related conditions – This could help in planning both pre and post-transplant rehab with focus on existing functional incapacity and to also differentiate the difference between post-transplant complications and existing conditions. 

  • Occupation – Discussing return to work (if applicable) at the initial assessment can help PT’s understand the area which needs more focus during rehab and perhaps plan an early return to work depending upon patients individual medical and physical condition. If possible, some of the work related functional evaluation tests can be carried out at this stage and can be vital in not only monitoring but for making work related recommendations to the patients and their employers.

  • Medications –  The PT’s should make themselves aware of the history of medications and be aware of the potential side-effects. 


Upper Limb Functional Assessment (pdf)


Lower Limb Functional Assessment (pdf)



Mohammed J, Akomolafe T, Aljurf M, Savani B, Hashmi SK. ‘To treat or not to treat’: raising awareness on the effects of graft versus host disease drugs on musculoskeletal system. Bone marrow transplantation. 2018 Jan 25:1.

Mohammed J, AlGhamdi A, Hashmi SK. Full-body physical therapy evaluation for pre-and post-hematopoietic cell transplant patients and the need for a modified rehabilitation musculoskeletal specific grading system for chronic graft-versus-host disease. Bone marrow transplantation. 2018 May;53(5):62

Mohammed J, Aljurf M, Althumayri A, Almansour M, Alghamdi A, Hamidieh AA, ElHaddad A, Othman TB, Bazarbachi A, Almohareb F, Alzahrani M. Physical Therapy Pathway and Protocol for patients undergoing hematopoietic stem cell transplantation: Recommendations from The Eastern Mediterranean Blood and Marrow Transplantation (EMBMT) Group. Hematology/oncology and stem cell therapy. 2019 Jan 11.

Mohammed J, Smith SR, Burns L, Basak G, Aljurf M, SavaniMD BN, Schoemans H, Peric Z, Chaudhri NA, Chigbo N, Alfred A. Role of physical therapy pre and post hematopoietic stem cell transplantation–White paper report. Biology of Blood and Marrow Transplantation. 2019 Jan 15.